Automated description from the Alliance of Genome Resources
Predicted to have several functions, including amyloid-beta binding activity; low-density lipoprotein particle receptor binding activity; and misfolded protein binding activity. Involved in immune complex clearance; positive regulation of cell death; and regulation of protein metabolic process. Localizes to several cellular components, including the cytosol; mitochondrion; and synapse. Predicted to colocalize with the cell periphery; cytoskeleton; and membrane. Human ortholog(s) of this gene implicated in artery disease (multiple); breast cancer; diabetic retinopathy; exfoliation syndrome; and muscular disease (multiple). Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human CLU (clusterin).