Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits calcium ion binding activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; nervous system development; and regulation of signal transduction. Localizes to several cellular components, including basolateral plasma membrane; fascia adherens; and sarcolemma. Predicted to colocalize with cortical actin cytoskeleton. Is expressed in several structures, including alimentary system; embryo mesenchyme; intervertebral disc; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular cardiomyopathy. Orthologous to human CDH2 (cadherin 2).