Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits SH3 domain binding activity and ephrin receptor binding activity. Involved in regulation of Rap protein signal transduction and regulation of platelet-derived growth factor receptor-alpha signaling pathway. Localizes to Golgi apparatus and cilium. Colocalizes with flotillin complex. Is expressed in male reproductive system and urinary system. Human ortholog(s) of this gene implicated in acute myeloid leukemia; juvenile myelomonocytic leukemia; lung non-small cell carcinoma; and myeloid neoplasm. Orthologous to human CBL (Cbl proto-oncogene).