Automated description from the Alliance of Genome Resources
Exhibits SH3 domain binding activity and ephrin receptor binding activity. Involved in regulation of Rap protein signal transduction and regulation of platelet-derived growth factor receptor-alpha signaling pathway. Localizes to the Golgi apparatus and cilium. Colocalizes with the flotillin complex. Human ortholog(s) of this gene implicated in acute myeloid leukemia; juvenile myelomonocytic leukemia; lung non-small cell carcinoma; and myeloid neoplasm. Is expressed in male reproductive system and urinary system. Orthologous to human CBL (Cbl proto-oncogene).