Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have several functions, including DNA binding activity; NF-kappaB binding activity; and nuclease activity. Involved in cell redox homeostasis. Localizes to cytoplasm and nucleus. Is expressed in several structures, including alimentary system; autopod; musculoskeletal system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in breast cancer; female reproductive organ cancer (multiple); spina bifida; and urinary bladder cancer. Orthologous to human APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1).