Automated description from the Alliance of Genome Resources
A structural constituent of cytoskeleton. Involved in hemopoiesis and synapse assembly. Localizes to the membrane and postsynaptic density. Used to study hereditary spherocytosis type 1. Human ortholog(s) of this gene implicated in IgA glomerulonephritis and hypertension. Is expressed in several structures, including central nervous system; liver; retina; spinal ganglion; and turbinate bone primordium. Orthologous to human ADD2 (adducin 2).