Automated description from the Alliance of Genome Resources (Release 7.0.0)
Contributes to acetylcholine-gated monoatomic cation-selective channel activity. Acts upstream of or within regulation of membrane potential. Located in postsynaptic membrane. Is active in neuromuscular junction and postsynaptic specialization membrane. Is expressed in diaphragm; skeletal musculature; and tongue. Used to study congenital myasthenic syndrome 4A and congenital myasthenic syndrome 4C. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome; congenital myasthenic syndrome 4A; congenital myasthenic syndrome 4B; and congenital myasthenic syndrome 4C. Orthologous to human CHRNE (cholinergic receptor nicotinic epsilon subunit).