Automated description from the Alliance of Genome Resources (Release 7.0.0)
Contributes to ubiquitin protein ligase activity. Acts upstream of or within several processes, including ovarian follicle development; protein ubiquitination; and spermatogenesis. Part of Fanconi anaemia nuclear complex. Used to study primary ovarian insufficiency. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group F; adenocarcinoma in situ; and granulosa cell tumor. Orthologous to human FANCF (FA complementation group F).