Automated description from the Alliance of Genome Resources (Release 7.1.0)
Enables omega-hydroxyceramide transacylase activity. A structural constituent of skin epidermis. Involved in establishment of skin barrier; keratinocyte differentiation; and omega-hydroxyceramide biosynthetic process. Predicted to be active in cytoplasm; lipid droplet; and membrane. Is expressed in gut; heart; liver; skin; and spleen. Used to study autosomal recessive congenital ichthyosis 10. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 10. Orthologous to human PNPLA1 (patatin like phospholipase domain containing 1).