Automated description from the Alliance of Genome Resources (Release 5.2.0)
Enables GTPase activator activity. Involved in maintenance of postsynaptic specialization structure. Acts upstream of or within several processes, including negative regulation of axonogenesis; regulation of long-term neuronal synaptic plasticity; and visual learning. Located in dendritic shaft; membrane; and postsynaptic density. Is active in glutamatergic synapse. Used to study schizophrenia. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 5. Orthologous to human SYNGAP1 (synaptic Ras GTPase activating protein 1).