Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables serine-type endopeptidase activity. Acts upstream of or within several processes, including acute inflammatory response to antigenic stimulus; response to fungus; and response to lipopolysaccharide. Located in cytoplasm. Human ortholog(s) of this gene implicated in cyclic hematopoiesis; periodontitis; polycythemia vera; severe congenital neutropenia; and severe congenital neutropenia 1. Orthologous to human ELANE (elastase, neutrophil expressed).