Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits serine-type endopeptidase activity. Involved in several processes, including acute inflammatory response to antigenic stimulus; response to fungus; and response to lipopolysaccharide. Localizes to cytoplasm. Human ortholog(s) of this gene implicated in cyclic hematopoiesis; periodontitis; polycythemia vera; severe congenital neutropenia; and severe congenital neutropenia 1. Orthologous to human ELANE (elastase, neutrophil expressed).