Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable mechanosensitive monoatomic ion channel activity; protein sequestering activity; and tumor necrosis factor binding activity. Predicted to be involved in intracellular zinc ion homeostasis; negative regulation of protein-containing complex assembly; and regulation of extrinsic apoptotic signaling pathway via death domain receptors. Predicted to act upstream of or within monoatomic ion transmembrane transport. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and nuclear membrane. Human ortholog(s) of this gene implicated in epidermodysplasia verruciformis. Orthologous to human TMC8 (transmembrane channel like 8).