Automated description from the Alliance of Genome Resources (Release 4.0)
Is predicted to enable DNA polymerase binding activity. Involved in DNA repair; mitotic intra-S DNA damage checkpoint signaling; and response to gamma radiation. Acts upstream of or within several processes, including homologous chromosome pairing at meiosis; neuronal stem cell population maintenance; and regulation of regulatory T cell differentiation. Located in condensed chromosome and nucleus. Used to study Fanconi anemia complementation group D2. Human ortholog(s) of this gene implicated in Fanconi anemia; Fanconi anemia complementation group D2; and breast cancer. Orthologous to human FANCD2 (FA complementation group D2).