Automated description from the Alliance of Genome Resources (Release 5.2.2)
Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; beta-catenin binding activity; and histone methyltransferase activity (H3-K4 specific). Involved in several processes, including histone H3-K4 methylation; regulation of chromatin organization; and regulation of erythrocyte differentiation. Acts upstream of or within positive regulation of neural precursor cell proliferation; positive regulation of stem cell proliferation; and stem cell population maintenance. Located in euchromatin and nucleus. Is expressed in several structures, including early conceptus; integumental system; liver; nervous system; and oocyte. Orthologous to human SETD1A (SET domain containing 1A, histone lysine methyltransferase).