Automated description from the Alliance of Genome Resources (Release 3.2)
Involved in several processes, including axon extension; phagosome-lysosome fusion involved in apoptotic cell clearance; and walking behavior. Localizes to several cellular components, including axon; cytosol; and dendrite. Used to study hereditary spastic paraplegia 11. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2X; amyotrophic lateral sclerosis type 5; and hereditary spastic paraplegia 11. Orthologous to human SPG11 (SPG11 vesicle trafficking associated, spatacsin).