Automated description from the Alliance of Genome Resources (Release 5.2.0)
Predicted to enable protein kinase binding activity. Acts upstream of or within several processes, including axonogenesis; cholesterol efflux; and motor neuron apoptotic process. Located in several cellular components, including axon; cytosol; and dendrite. Used to study hereditary spastic paraplegia 11. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2X; amyotrophic lateral sclerosis type 5; and hereditary spastic paraplegia 11. Orthologous to human SPG11 (SPG11 vesicle trafficking associated, spatacsin).