Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables calcium-dependent phospholipase A2 activity. Involved in several processes, including positive regulation of histamine secretion by mast cell; positive regulation of mast cell differentiation; and positive regulation of prostaglandin biosynthetic process. Acts upstream of or within several processes, including negative regulation of amyloid-beta clearance; regulation of gene expression; and spermatid development. Predicted to be located in centriole and recycling endosome. Is expressed in several structures, including alimentary system; cranium; genitourinary system; integumental system; and nervous system. Orthologous to human PLA2G3 (phospholipase A2 group III).