Automated description from the Alliance of Genome Resources
Exhibits 5'-flap endonuclease activity. Involved in mitotic telomere maintenance via semi-conservative replication and nucleic acid phosphodiester bond hydrolysis. Localizes to the nuclear chromosome, telomeric region. Predicted to colocalize with the gamma DNA polymerase complex. Human ortholog(s) of this gene implicated in Seckel syndrome 8; chronic progressive external ophthalmoplegia; isolated growth hormone deficiency type IA; and mitochondrial myopathy. Orthologous to human DNA2 (DNA replication helicase/nuclease 2).