Automated description from the Alliance of Genome Resources
Predicted to have several functions, including 2-oxoglutarate-dependent dioxygenase activity; NF-kappaB binding activity; and transition metal ion binding activity. Predicted to be involved in several processes, including negative regulation of Notch signaling pathway; negative regulation of transcription from RNA polymerase II promoter in response to hypoxia; and protein hydroxylation. Predicted to localize to the cytosol; nucleoplasm; and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and skeletal muscle. Orthologous to human HIF1AN (hypoxia inducible factor 1 subunit alpha inhibitor).