Automated description from the Alliance of Genome Resources (Release 4.1.0)
Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including positive regulation of cellular component organization; positive regulation of nitrogen compound metabolic process; and positive regulation of transport. Predicted to act upstream of or within angiogenesis. Predicted to be located in several cellular components, including basolateral part of cell; brush border membrane; and distal axon. Predicted to colocalize with cortical actin cytoskeleton and plasma membrane. Is expressed in brain; heart; lung; and metanephros. Orthologous to human RAPGEF3 (Rap guanine nucleotide exchange factor 3).