Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable GDP binding activity; GTP binding activity; and identical protein binding activity. Predicted to contribute to guanyl-nucleotide exchange factor activity and translation initiation factor activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; oligodendrocyte development; and response to amino acid starvation. Predicted to be located in cytoplasm and plasma membrane. Predicted to be part of eukaryotic translation initiation factor 2 complex and eukaryotic translation initiation factor 2B complex. Is expressed in several structures, including cranium; nervous system; physiological umbilical hernia; submandibular gland primordium; and thoracic intervertebral disc. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter 1. Orthologous to human EIF2B1 (eukaryotic translation initiation factor 2B subunit alpha).