Automated description from the Alliance of Genome Resources (Release 4.1.0)
Enables several functions, including DNA-binding transcription factor activity; actin monomer binding activity; and transcription coactivator activity. Involved in actin cytoskeleton organization and positive regulation of transcription via serum response element binding activity. Acts upstream of or within negative regulation of apoptotic process; nervous system development; and positive regulation of transcription, DNA-templated. Located in cytoplasm and nucleus. Is expressed in cerebellum; early conceptus; liver; oocyte; and telencephalon. Human ortholog(s) of this gene implicated in acute megakaryocytic leukemia and immunodeficiency 66. Orthologous to human MRTFA (myocardin related transcription factor A).