Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables several functions, including DNA-binding transcription factor activity; actin monomer binding activity; and transcription coactivator activity. Involved in actin cytoskeleton organization and positive regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of apoptotic process; nervous system development; and positive regulation of DNA-templated transcription. Located in cytoplasm and nucleus. Is expressed in brain; early conceptus; liver; and oocyte. Human ortholog(s) of this gene implicated in acute megakaryocytic leukemia and immunodeficiency 66. Orthologous to human MRTFA (myocardin related transcription factor A).