Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables ubiquitin protein ligase activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein K48-linked ubiquitination. Predicted to be located in cytosol and endosome. Predicted to be active in cytoplasm; intracellular membrane-bounded organelle; and membrane. Is expressed in several structures, including central nervous system; genitourinary system; and retina nuclear layer. Orthologous to human ZNRF1 (zinc and ring finger 1).