Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables small GTPase binding activity. A structural constituent of presynaptic active zone. Involved in regulation of calcium-dependent activation of synaptic vesicle fusion; regulation of presynaptic cytosolic calcium ion concentration; and synaptic vesicle priming. Acts upstream of or within retrograde transport, endosome to Golgi. Located in cytoplasm and synapse. Is active in GABA-ergic synapse; glutamatergic synapse; and presynaptic cytosol. Is expressed in several structures, including genitourinary system; gut gland; oral epithelium; retina; and telencephalon. Orthologous to human ERC1 (ELKS/RAB6-interacting/CAST family member 1).