Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to have several functions, including DNA topoisomerase binding activity; antigen binding activity; and ubiquitin-like protein transferase activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; positive regulation of transcription, DNA-templated; and regulation of cell population proliferation. Localizes to ciliary basal body; nucleus; and photoreceptor connecting cilium. Human ortholog(s) of this gene implicated in retinitis pigmentosa 31. Is expressed in skin. Orthologous to human TOPORS (TOP1 binding arginine/serine rich protein).