Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity. Acts upstream of or within parturition and progesterone catabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Is expressed in several structures, including adrenal gland; brain; female reproductive system; and lung. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; T-cell acute lymphoblastic leukemia; and leukemia. Orthologous to human AKR1C3 (aldo-keto reductase family 1 member C3).