GO curators for mouse genes have assigned the following annotations to the gene product of Cog5. (This text reflects annotations as of Wednesday, January 23, 2013.) MGI curation of this mouse gene is considered complete, including annotations derived from the biomedical literature as of February 9, 2010. If you know of any additional information regarding this mouse gene please let us know. Please supply mouse gene symbol and a PubMed ID.Summary from NCBI RefSeq
[Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. The encoded protein is organized with conserved oligomeric Golgi complex components 6, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants. Mutations in this gene result in congenital disorder of glycosylation type 2I.[provided by RefSeq, Jan 2011]Summary text based on GO annotations supported by experimental evidence in other organisms
From comparative sequence analysis (see table for details), MGI curators have determined that the gene product of Cog5:
participates in the following biological processes:
Annotations directly to molecular function for the gene Cog5 indicate that MGI curators have found no experimental data [literature] to support further annotation to this category at this time.
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