Automated description from the Alliance of Genome Resources (Release 5.2.2)
Enables histone methyltransferase activity (H3-K27 specific) and histone methyltransferase activity (H3-K4 specific). Acts upstream of or within negative regulation of DNA-templated transcription. Predicted to be located in chromosome. Predicted to be active in chromatin and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and liver and biliary system. Human ortholog(s) of this gene implicated in myeloid leukemia. Orthologous to human NSD3 (nuclear receptor binding SET domain protein 3).