Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits histone methyltransferase activity (H3-K27 specific) and histone methyltransferase activity (H3-K4 specific). Involved in negative regulation of transcription, DNA-templated. Predicted to localize to chromatin and nucleus. Is expressed in metanephros and renal vasculature. Human ortholog(s) of this gene implicated in myeloid leukemia. Orthologous to human NSD3 (nuclear receptor binding SET domain protein 3).