Automated description from the Alliance of Genome Resources
Exhibits apolipoprotein binding activity; lipoprotein particle binding activity; and low-density lipoprotein particle receptor binding activity. Involved in several processes, including animal organ development; cellular response to insulin stimulus; and regulation of low-density lipoprotein particle receptor catabolic process. Localizes to the COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum; and extracellular space. Human ortholog(s) of this gene implicated in hypobetalipoproteinemia. Orthologous to human PCSK9 (proprotein convertase subtilisin/kexin type 9).