Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have several functions, including ARF guanyl-nucleotide exchange factor activity; GABA receptor binding activity; and protein kinase A regulatory subunit binding activity. Predicted to be involved in several processes, including Golgi to plasma membrane transport; positive regulation of tumor necrosis factor production; and receptor recycling. Predicted to localize to several cellular components, including Golgi apparatus; dendritic spine; and microtubule cytoskeleton. Is expressed in brown fat; central nervous system; duodenum; thymus; and trunk. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2).