Automated description from the Alliance of Genome Resources
Exhibits DNA helicase activity. Involved in DNA unwinding involved in DNA replication and mitochondrial DNA replication. Localizes to the mitochondrion. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in Perrault syndrome; chronic progressive external ophthalmoplegia; and mitochondrial DNA depletion syndrome 7. Orthologous to human TWNK (twinkle mtDNA helicase).