Automated description from the Alliance of Genome Resources
Exhibits ubiquitin protein ligase activity. Involved in cellular response to leukemia inhibitory factor and regulation of neuron apoptotic process. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2R. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human TRIM2 (tripartite motif containing 2).