Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits several functions, including identical protein binding activity; protein phosphatase binding activity; and protein serine/threonine kinase activity. Involved in several processes, including dendritic cell proliferation; positive regulation of response to biotic stimulus; and regulation of gene expression. Predicted to localize to cytoplasm and nucleoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in brain disease and frontotemporal dementia and/or amyotrophic lateral sclerosis-4. Orthologous to human TBK1 (TANK binding kinase 1).