Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable ATP-activated inward rectifier potassium channel activity; ion binding activity; and peptide binding activity. Acts upstream of or within several processes, including kidney development; renal sodium ion absorption; and tissue homeostasis. Predicted to be located in membrane. Predicted to be part of monoatomic ion channel complex. Predicted to be active in plasma membrane. Is expressed in heart and metanephros. Used to study Bartter disease type 2. Human ortholog(s) of this gene implicated in Bartter disease type 2. Orthologous to human KCNJ1 (potassium inwardly rectifying channel subfamily J member 1).