Automated description from the Alliance of Genome Resources
Exhibits several functions, including SH2 domain binding activity; calcium channel activity; and osmosensor activity. Involved in several processes, including cellular response to osmotic stress; positive regulation of MAPK cascade; and positive regulation of cytokine production. Localizes to the adherens junction; cilium; and plasma membrane. Predicted to colocalize with the cytoplasmic microtubule. Used to study autosomal dominant nonsyndromic deafness 25. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2C and osteonecrosis. Orthologous to human TRPV4 (transient receptor potential cation channel subfamily V member 4).