Go Annotations as Summary Text (Tabular View) (GO Graph)

GO curators for mouse genes have assigned the following annotations to the gene product of Treh. (This text reflects annotations as of Tuesday, May 21, 2013.)

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Summary from NCBI RefSeq

This gene belongs to the alpha-glucosidase family, whose members encode enzymes that carry out hydrolysis of alpha-glucoside bonds of a variety of carbohydrates. The enzyme encoded by this gene uses the disaccharide trehalose as a highly specific substrate and converts it into two glucose molecules. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2013]

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Summary text based on GO annotations supported by experimental evidence in other organisms

• From comparative sequence analysis (see table for details), MGI curators have determined that the gene product of Treh:
  • participates in the following biological processes:
    • organ morphogenesis
  • performs the following molecular functions:
    • alpha,alpha-trehalase activity

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Summary text based on GO annotations supported by structural data

• Treh encodes a protein or proteins that contain the following InterPro domains: Glycoside hydrolase, family 37, Glycoside hydrolase, family 37, conserved site, Six-hairpin glycosidase-like, indicating that the gene product:
  • participates in the following biological processes:
    • trehalose metabolic process
  • performs the following molecular functions:
    • catalytic activity

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Summary text for additional MGI annotations

• Automated translation to GO terms of SwissProt keywords that describe Treh indicates that it:
  • participates in the following biological processes:
    • metabolic process
  • performs the following molecular functions:
    • hydrolase activity
    • hydrolase activity, acting on glycosyl bonds
  • is located in the following cellular components:
    • anchored to membrane
    • membrane
    • plasma membrane

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Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISS Inferred from sequence or structural similarity

ISO Inferred from sequence orthology

ISA Inferred from sequence alignment

ISM Inferred from sequence model

NAS Non-traceable author statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

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