GO curators for mouse genes have assigned the following annotations to the gene product of Rsph9. (This text reflects annotations as of Thursday, July 24, 2014.) MGI curation of this mouse gene is considered complete, including annotations derived from the biomedical literature as of February 9, 2010. If you know of any additional information regarding this mouse gene please let us know. Please supply mouse gene symbol and a PubMed ID.Summary from NCBI RefSeq
[Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein thought to be a component of the radial spoke head in motile cilia and flagella. Mutations in this gene are associated with primary ciliary dyskinesia 12. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]Summary text based on GO annotations supported by experimental evidence in mouse
Researchers have inferred, based on genetic interactions, that the gene product of Rsph9
participates in the following biological processes:
Annotations directly to molecular function for the gene Rsph9 indicate that MGI curators have found no experimental data [literature] to support further annotation to this category at this time.
Castleman VH et al. (2009) Mutations in radial spoke head protein genes RSPH9 and RSPH4A cause primary ciliary dyskinesia with central-microtubular-pair abnormalities. Am J Hum Genet, 84:197-209. (PubMed:19200523)