Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including DNA binding activity; DNA topoisomerase binding activity; and histone H3 methyltransferase activity. Predicted to be involved in several processes, including DNA metabolic process; mitotic DNA integrity checkpoint signaling; and positive regulation of double-strand break repair via nonhomologous end joining. Predicted to act upstream of or within chromatin organization and methylation. Predicted to be located in nucleolus and site of double-strand break. Predicted to colocalize with condensed chromosome. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and respiratory system. Orthologous to human SETMAR (SET domain and mariner transposase fusion gene).