Automated description from the Alliance of Genome Resources
Predicted to have transcription factor binding activity. Involved in negative regulation of ossification; negative regulation of signal transduction; and ossification. Predicted to localize to the Golgi apparatus; extracellular space; and protein-containing complex. Used to study SOST-related sclerosing bone dysplasia and sclerosteosis 1. Human ortholog(s) of this gene implicated in SOST-related sclerosing bone dysplasia; sclerosteosis; and sclerosteosis 1. Is expressed in arterial system; jaw; and skeleton. Orthologous to human SOST (sclerostin).