Automated description from the Alliance of Genome Resources
Exhibits protein self-association. Involved in nuclear membrane organization. Localizes to the endoplasmic reticulum lumen and integral component of nuclear inner membrane. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular cardiomyopathy; arrhythmogenic right ventricular dysplasia 5; and autosomal dominant Emery-Dreifuss muscular dystrophy 7. Orthologous to human TMEM43 (transmembrane protein 43).