Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable mitogen-activated protein kinase kinase kinase binding activity. Acts upstream of or within cell-cell junction organization; negative regulation of epithelial cell migration; and negative regulation of epithelial cell proliferation. Located in bicellular tight junction. Is expressed in brain ventricle and choroid plexus; foregut; renal calyx; retina; and trachea. Orthologous to human MARVELD3 (MARVEL domain containing 3).