Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell dedifferentiation; regulation of DNA-templated transcription; and regulation of neurogenesis. Acts upstream of or within nervous system development and positive regulation of neuron differentiation. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including brain and nose. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 22 with or without anosmia. Orthologous to human FEZF1 (FEZ family zinc finger 1).