Automated description from the Alliance of Genome Resources
Involved in several processes, including cilium assembly; growth; and regulation of smoothened signaling pathway. Localizes to the axoneme; ciliary basal body; and nucleus. Used to study Kallmann syndrome and ciliopathy. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 14 with or without anosmia. Is expressed in several structures, including central nervous system; frontal bone primordium; metanephros; otic capsule; and submandibular gland primordium. Orthologous to human WDR11 (WD repeat domain 11).