Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits frizzled binding activity and heparin binding activity. Involved in several processes, including blood vessel remodeling; branching involved in labyrinthine layer morphogenesis; and positive regulation of Wnt signaling pathway. Localizes to extracellular region. Is expressed in several structures, including central nervous system; genitourinary system; heart; limb; and skeleton. Orthologous to human RSPO3 (R-spondin 3).