Automated description from the Alliance of Genome Resources (Release 3.0)
Involved in myotube differentiation and regulation of cellular protein metabolic process. Localizes to A band; Cul3-RING ubiquitin ligase complex; and I band. Used to study nemaline myopathy 8. Human ortholog(s) of this gene implicated in nemaline myopathy 8. Is expressed in several structures, including diaphragm; genitourinary system; limb segment; musculature; and paraxial mesenchyme. Orthologous to human KLHL40 (kelch like family member 40).