Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to have myosin tail binding activity and spectrin binding activity. Involved in several processes, including brush border assembly; inner ear development; and parallel actin filament bundle assembly. Localizes to several cellular components, including brush border; photoreceptor inner segment; and photoreceptor outer segment. Predicted to colocalize with photoreceptor connecting cilium. Used to study Usher syndrome type 1C and autosomal recessive nonsyndromic deafness 18A. Human ortholog(s) of this gene implicated in Usher syndrome; Usher syndrome type 1; Usher syndrome type 1C; and autosomal recessive nonsyndromic deafness 18A. Is expressed in several structures, including alimentary system; cochlea; genitourinary system; heart; and lung epithelium. Orthologous to human USH1C (USH1 protein network component harmonin).