Automated description from the Alliance of Genome Resources (Release 4.0)
Predicted to have myosin tail binding activity and spectrin binding activity. Involved in several processes, including brush border assembly; inner ear development; and parallel actin filament bundle assembly. Localizes to several cellular components, including brush border; photoreceptor inner segment; and upper tip-link density. Predicted to colocalize with photoreceptor connecting cilium. Is expressed in several structures, including alimentary system; cochlea; genitourinary system; heart; and lung epithelium. Used to study Usher syndrome type 1C and autosomal recessive nonsyndromic deafness 18A. Human ortholog(s) of this gene implicated in Usher syndrome; Usher syndrome type 1; Usher syndrome type 1C; and autosomal recessive nonsyndromic deafness 18A. Orthologous to human USH1C (USH1 protein network component harmonin).