Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits several functions, including SMAD binding activity; histone methyltransferase activity (H3-K9 specific); and transcription coactivator activity. Involved in several processes, including brown fat cell differentiation; positive regulation of brown fat cell differentiation; and regulation of transcription, DNA-templated. Localizes to nucleus and transcriptional repressor complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; embryo mesenchyme; and sensory organ. Orthologous to human PRDM16 (PR/SET domain 16).