Automated description from the Alliance of Genome Resources
Exhibits DNA binding activity. Involved in DNA replication checkpoint; regulation of DNA-dependent DNA replication initiation; and regulation of nuclear cell cycle DNA replication. Localizes to the nucleus. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 4. Is expressed in adrenal medulla; brain ventricular layer; dorsal root ganglion; and trunk mesenchyme derived from neural crest. Orthologous to human CDT1 (chromatin licensing and DNA replication factor 1).