Automated description from the Alliance of Genome Resources
Predicted to have calcium ion binding activity. Involved in negative regulation of tooth mineralization and negative regulation of transforming growth factor beta receptor signaling pathway. Localizes to the extracellular matrix. Human ortholog(s) of this gene implicated in ankylosing spondylitis; degenerative disc disease; and osteoarthritis. Is expressed in several structures, including alimentary system; forelimb; integumental system; reproductive system; and skeleton. Orthologous to human ASPN (asporin).