Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have several functions, including identical protein binding activity; ubiquitin binding activity; and ubiquitin-protein transferase activity. Involved in several processes, including apoptotic nuclear changes; keratinization; and regulation of signal transduction. Predicted to localize to several cellular components, including LUBAC complex; dendrite; and postsynaptic density. Is expressed in genitourinary system. Used to study atopic dermatitis. Orthologous to human SHARPIN (SHANK associated RH domain interactor).