Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to have ion channel binding activity. Predicted to be involved in cellular protein metabolic process; negative regulation of ion transmembrane transport; and regulation of protein-containing complex assembly. Predicted to localize to Cul4A-RING E3 ubiquitin ligase complex; nucleus; and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; aorta; central nervous system; eye; and genitourinary system. Used to study autosomal recessive non-syndromic intellectual disability. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human CRBN (cereblon).