Automated description from the Alliance of Genome Resources
Predicted to have metal ion binding activity. Predicted to be involved in several processes, including cellular protein metabolic process; negative regulation of protein homooligomerization; and positive regulation of protein homodimerization activity. Predicted to localize to the Cul4A-RING E3 ubiquitin ligase complex; cytoplasm; and nucleus. Used to study autosomal recessive non-syndromic intellectual disability. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Is expressed in several structures, including alimentary system; aorta; central nervous system; eye; and genitourinary system. Orthologous to human CRBN (cereblon).