Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits Rac guanyl-nucleotide exchange factor activity and epidermal growth factor receptor binding activity. Involved in several processes, including integrin-mediated signaling pathway; neutrophil chemotaxis; and positive regulation of phosphatidylinositol 3-kinase activity. Localizes to cytoplasm and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; limb segment; metanephros; and sensory organ. Orthologous to human VAV3 (vav guanine nucleotide exchange factor 3).